Quality level: 200
Biological source: synthetic
Mp: > 290 ° C
DMSO: 10 mg / ml
Storage temperature: −20 ° C
SMILES chain: Oc1ccc (cc1) C2 = COc3cc (O) ccc3C2 = O
InChI: 1S / C15H10O4 / c16-10-3-1-9 (2-4-10) 13-8-19-14-7-11 (17) 5-6-12 (14) 15 (13) 18 / h1- 8.16-17H
InChI key: ZQSIJRDFPHDXIC-UHFFFAOYSA-N
Daidzein is an isoflavone found in soybeans. Regulates oxidative stress, angiogenesis, cell growth, and apoptosis. Daidzein has antioxidant, antiestrogenic, and antiatherogenic properties. Provides protection against osteoporosis.
Daidzein has been used:
- as a control to assess fertility in rats
- to study its effects on ovarian cancer
- to stimulate antioxidant activity in vitro
- 25 mg in a polyethylene bottle
- 100 mg in a glass bottle
- Packed under argon.
Biochemical / Physiological Actions
The soy isoflavone daidzein protects against oxidative damage to liver cells induced by 7,12-dimethy lbenzo [a] anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein. Daidzein is a phytoestrogen that is suggested to play a role in the prevention of hormone-induced cancers. Stops the cell cycle at G1 in Swiss 3T3 cells.
Features and Benefits
This compound is also offered as part of Sigma’s Library of Pharmacologically Active Compounds (LOPAC®1280), a biological annotation collection of high-quality, ready-to-test compounds. Click here to find out more.
LOPAC is a registered trademark of Sigma-Aldrich Co. LLC